Subset and filter multiple pathway matrices to match target genes

Filters gene-by-pathway annotation matrices to retain only pathways with sufficient overlap with a given gene set. The result is a sparse matrix aligned to new.genes, combining all inputs column-wise.

getMatchedPathwayMat2(..., new.genes, min.genes = 10)

Arguments

...

One or more sparse binary matrices (genes x pathways).

new.genes

Character vector of gene names to match.

min.genes

Minimum number of overlapping genes required to keep a pathway.

Value

A sparse matrix with rows = new.genes and columns = filtered pathways from all inputs.